Vessels
- 70L
- 80L
- 250L
- 500L
- 1,600L
A free standing 70 liter scale up/seed vessel that is capable of routine working volumes of between 30-50 liters. This 70L vessel is manually controlled and monitored for temperature, pH, O2 and turbidity. This vessel can be used for small scale production, a testing platform for scale up and protocol optimization, or as a seed build tank for our larger production vessels.
A separate 500 liter production vessel with working volumes of between 200-450 liters is also available for contract applications. This vessel is ideal for small multiple batch production runs where final customers may be emerging niche markets with an initial limited distribution. The 500L vessel is manually controlled and monitored for temperature, pH, O2, and turbidity. Customers also request the 500L vessel when requiring larger volumes of working material to adapt their proprietary laboratory scale downstream process to a more robust production protocol needed for large scale commercialization of their product.
The 1,600 liter production vessel has working volumes of between 1,000-1,400 liters. The vessel is configured in a production module which includes an 80L acid addition make-up tank, an 80L base addition make-up tank, a 16L auxiliary tank for miscellaneous additions, the 1,600L batch fermentor tank, and the PLC controller module for automated control and monitoring the fermentation run. The design of the PLC controller allows for automated cascading of aeration, agitation, and vessel pressure, and to control % DO at a specified range. The PLC controller is flexibly designed to allow for custom configurations of a given client's control scheme and production protocol. CO2 off-gas measurements can also be provided for clients requesting a more detailed profile of a specific organism's metabolism.
The 1,600 liter vessel is the ideal pilot plant and medium scale production vessel. With the PLC controller we can program our client's process parameters and subsequently capture process data for batch records and reports required for cGMP compliance. The controller's advanced software also provides real time graphic representation of the fermentation process and results. Cost efficiencies of batch processing and the commercial scalability of protocols for large scale industrial products can be optimized with our 1,600L vessel. It is ideal for pilot cGMP protocols and it is routinely used for medium volume production of material for various commercial applications.